Thermo Fisher Scientific USP12 Polyclonal Antibody
USP12 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot과 IHC에 적합하며 Human, Mouse 반응성. 고순도 affinity chromatography 정제, 안정적 PBS/glycerol buffer 제공, 연구용으로만 사용 가능.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:2,000 | View 1 publication |
| Immunohistochemistry (IHC) | – | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:25–1:100 | View publication |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Full-length fusion protein of human USP12 (UniProt ID: O75317-1, antigen range: 1–370) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.9 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | –20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2692241 |
Target Information
Deubiquitinating enzyme USP12 has almost no deubiquitinating activity by itself and requires interaction with WDR20 and WDR48 for high activity (PubMed:19075014, PubMed:27373336). It is not involved in deubiquitination of monoubiquitinated FANCD2 (PubMed:19075014). In complex with WDR48, USP12 acts as a potential tumor suppressor by positively regulating PHLPP1 stability (PubMed:24145035). [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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