Thermo Fisher Scientific Human BAP31 Synthetic Peptide
인간 BAP31 단백질의 C-말단 17개 아미노산 서열로 구성된 합성 펩타이드. 항체 PA5-20194의 블로킹 펩타이드로 사용 가능. 정제된 액상 형태로 PBS(pH 7.2) 및 0.1% BSA 함유. -20°C에서 보관.
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 17 amino acids near the carboxy terminus of human BAP31.
PEP-0324 can be used as a blocking peptide with polyclonal antibody PA5-20194.
Target Information
BAP31 (B-Cell Receptor Associated Protein, 31-kDa) is a multiple membrane-spanning protein of the endoplasmic reticulum. It forms both homo- and hetero-oligomers with BAP29 and acts as a potential apoptotic regulator associated with BCL-2/BCL-XL.
The C-terminal domain of BAP31 contains two identical recognition sites for initiator Caspases 1 and 8, involved in the programmed cell death cascade.
BAP31 is hypothesized to play a role in the transport of selected proteins to the Golgi apparatus and regulates CFTR (cystic fibrosis transmembrane conductance regulator) expression.
Interference with BAP31 function in epithelial cells may help circumvent chloride channel defects in cystic fibrosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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