Thermo Fisher Scientific NLGN1/NLGN2 Polyclonal Antibody
NLGN1/NLGN2 단백질을 인식하는 Rabbit Polyclonal 항체로, IHC, ICC, Flow, ELISA 등 다양한 분석에 사용 가능. Human, Mouse, Rat 시료에 반응하며, Protein A 정제 및 고순도 보장. 연구용으로 신경 시냅스 단백질 연구에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:500 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| Flow Cytometry (Flow) | 1:100 |
| ELISA | 1:5,000–1:10,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human NLGN2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Neuroligins are a family of plasma membrane proteins that possess an N-terminal hydrophobic domain, a large esterase homology domain, a single transmembrane region, a short cytoplasmic domain, and an EF-hand binding domain. Members of this family include Neuroligin 1, Neuroligin 2, and Neuroligin 3. Neuroligins are expressed in excitatory neuronal synaptic clefts and play a key role in the formation and remodeling of CNS synapses by binding to β-neurexins, a family of neuronal cell surface proteins. Neuroexin 1β binds to the EF-hand domain of Neuroligin 1 in a calcium-dependent manner. Neuroligins also interact with PSD-95, which may help recruit ion channels and neurotransmitter receptors to the synapses.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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