Thermo Fisher Scientific USP13 Recombinant Rabbit Monoclonal Antibody (23GB4250)
USP13 단백질을 인식하는 재조합 토끼 단클론 항체로, WB, ICC/IF, Flow Cytometry에 사용 가능. HEK293F 시스템에서 발현되었으며, 고순도 친화 크로마토그래피 정제. PBS/glycerol 버퍼에 보관하며 -20°C에서 안정적.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:5,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:1,000
Flow Cytometry (Flow)
- Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293F |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 23GB4250 |
| Immunogen | A synthesized peptide derived from USP13 (750–800AA) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice (domestic); Dry ice (international) |
Target Information
Deubiquitinase that mediates deubiquitination of target proteins such as BECN1, MITF, SKP2, and USP10. Involved in autophagy and endoplasmic reticulum-associated degradation (ERAD). Regulates p53/TP53 levels through interaction with PIK3C3/VPS34-containing complexes and USP10. Recruited by nuclear UFD1 to mediate SKP2 deubiquitination, influencing ERAD processes. Also stabilizes SIAH2 independently of deubiquitinase activity. Preferentially cleaves Lys-63-linked polyubiquitin chains and may cleave ISG15 in vitro. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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