Thermo Fisher Scientific MRPS30 Polyclonal Antibody

Applications and Tested Dilutions

Product Specifications

Product Specific Information

Immunogen sequence:
FAWTGAQAMY QGFWSEADVT RPFVSQAVIT DGKYFSFFCY QLNTLALTTQ ADQNNPRKNI CWGTQSKPLY ETIEDNDVKG FNDDVLLQIV HFLLNRP

Antigen sequence identity:

• Mouse: 91%
• Rat: 94%

Target Information

Mitochondrial ribosomes consist of a large 39S subunit and a small 28S subunit, both composed of multiple mitochondrial ribosomal proteins (MRPs) encoded by nuclear genes essential for mitochondrial protein synthesis.
MRP-S30 (mitochondrial ribosomal protein S30), also known as PDCD9 (programmed cell death protein 9), is a 439 amino acid protein localized in the mitochondrion as part of the 28S ribosomal subunit. It functions with other MRPs to mediate mitochondrial protein synthesis.
MRP-S30 is expressed in kidney, liver, heart, and skeletal muscle. The MRPS30 gene maps to human chromosome 5, which contains 181 million base pairs and represents nearly 6% of the human genome. Deletion of the p arm of chromosome 5 causes Cri du chat syndrome, while deletion of the q arm or the entire chromosome 5 is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.

For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.