Thermo Fisher Scientific Ly-6E Polyclonal Antibody

Applications and Tested Dilution

• Immunocytochemistry (ICC/IF): 1:100–1:500

Product Specifications

Target Information

Sca1, also known as Ly6A/E, is a member of the Ly6 multigene family of type V glycophosphatidylinositol-anchored cell surface proteins. It is expressed on multipotent hematopoietic stem cells in the bone marrow of mice with both Ly6.1 and Ly6.2 allotypes.
In the periphery, Sca1 expression varies between the two allotypes:

• Ly6.1 strains (e.g., A, BALB/c, CBA, C3H/He, DBA/1, NZB) have few Sca1⁺ resting peripheral lymphocytes.
• Ly6.2 strains (e.g., AKR, C57BL, C57BR, C57L, DBA/2, PL, SJL, SWR, 129) have relatively high numbers of Sca1⁺ lymphocytes.
  Sca1 expression is dramatically upregulated in all strains upon cellular activation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.