
Thermo Fisher Scientific Ly-6E Polyclonal Antibody
Rabbit polyclonal antibody recognizing human LY6E 단백질. Immunocytochemistry에 적합하며, 고순도의 액상 형태로 제공. -20°C에서 보관, 연구용으로만 사용 가능.
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Applications and Tested Dilution
- Immunocytochemistry (ICC/IF): 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide derived from the internal region of human LY6E |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2555823 |
Target Information
Sca1, also known as Ly6A/E, is a member of the Ly6 multigene family of type V glycophosphatidylinositol-anchored cell surface proteins. It is expressed on multipotent hematopoietic stem cells in the bone marrow of mice with both Ly6.1 and Ly6.2 allotypes.
In the periphery, Sca1 expression varies between the two allotypes:
- Ly6.1 strains (e.g., A, BALB/c, CBA, C3H/He, DBA/1, NZB) have few Sca1⁺ resting peripheral lymphocytes.
- Ly6.2 strains (e.g., AKR, C57BL, C57BR, C57L, DBA/2, PL, SJL, SWR, 129) have relatively high numbers of Sca1⁺ lymphocytes.
Sca1 expression is dramatically upregulated in all strains upon cellular activation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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