Thermo Fisher Scientific JAB1 Polyclonal Antibody
JAB1 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western blot 및 IHC(P) 실험에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 고순도(>95%)를 유지합니다. Human, Mouse, Rat 시료에 반응하며, 연구용으로 사용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 160–212 of Human COPS5 / JAB1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2803221 |
Product Specific Information
Purity is greater than 95% by SDS-PAGE.
Target Information
JAB-1 is a 38 kDa protein originally described as a coactivator for cJUN. It is part of a large protein complex called the Signalosome, which is proposed to play a signaling role in mammalian cells. This complex is analogous to the COP9 complex in plants, important in light-mediated development. Although the specific function of JAB-1 in this complex is unclear, it has been implicated in targeting proteins for degradation by the proteasome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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