Thermo Fisher Scientific CD264 (TRAIL-R4) Recombinant Rabbit Monoclonal Antibody (201)

Applications and Tested Dilution

• Western Blot (WB): 1:500–1:1,000

Product Specifications

Product Specific Information

This product is preservative-free. It is recommended to add sodium azide (final concentration 0.05–0.1%) to prevent contamination.

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems by cloning specific antibody DNA sequences from immunoreactive rabbits. Individual clones are screened to select optimal candidates for production.

Advantages of recombinant rabbit monoclonal antibodies:

• Improved specificity and sensitivity
• Lot-to-lot consistency
• Animal origin-free formulations
• Broader immunoreactivity due to the large rabbit immune repertoire

This antibody specifically recognizes Human TRAIL R4/CD264/TNFRSF10D.

Target Information

TRAIL (also known as Apo-2L) is a member of the tumor necrosis factor (TNF) ligand family that induces apoptosis in various transformed cell lines.
TRAIL-R4, a member of the TRAIL receptor family, activates NF-κB similar to TRAIL-R1 and TRAIL-R2 but does not induce apoptosis.
Like TRAIL-R1 and TRAIL-R2, TRAIL-R4 is widely expressed across tissues.
The human TRAIL-R4 gene is located on chromosome 8p22-21, clustered with three other TRAIL receptors.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.