Thermo Fisher Scientific KCNMA1 Polyclonal Antibody
Thermo Fisher Scientific의 KCNMA1 Polyclonal Antibody는 마우스 KCa 1.1 단백질을 인식하는 rabbit IgG 항체로, WB, IHC, ICC, IP 등 다양한 응용에 적합합니다. Lyophilized 형태로 제공되며 -20°C 보관이 권장됩니다. 연구용으로만 사용 가능합니다.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500 | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-Dependent | - |
| Immunocytochemistry (ICC/IF) | Assay-Dependent | - |
| Immunoprecipitation (IP) | Assay-Dependent | - |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide (C)STANRPNRPKSRESRDK, corresponding to amino acid residues 1184–1200 of mouse KCa 1.1 |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.6 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2736009 |
Product Specific Information
This product is shipped at room temperature as a lyophilized powder and should be stored at -20°C upon receipt.
Reconstitution: Add 50 µL of deionized water.
Target Information
Potassium channels are ubiquitously expressed proteins serving numerous functions in excitable and non-excitable cells.
The large conductance, calcium-activated potassium channel (Maxi K⁺) is unique in that its activation is controlled by both intracellular calcium increase and membrane depolarization.
Maxi K⁺ channels consist of an alpha homotetramer containing a voltage sensor and an intracellular calcium binding domain.
In vascular smooth muscle, an auxiliary beta-subunit is present in a 1:1 ratio, reducing the calcium concentration required to keep the pore open by 5–10 fold.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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