
Thermo Fisher Scientific Bad Monoclonal Antibody (5D4)
BAD 단백질을 인식하는 Rabbit Monoclonal Antibody (Clone 5D4). Western blot 및 IHC(Paraffin) 검증 완료. 세포 사멸 조절 연구에 적합. 액상 형태, 1 mg/mL 농도, -20°C 보관.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 5D4 |
| Immunogen | Recombinant human Bad protein, full length |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
Target Information
The protein encoded by BAD is a member of the BCL-2 family, known regulators of programmed cell death. This protein promotes apoptosis by forming heterodimers with BCL-xL and BCL-2, reversing their death repressor activity. Its proapoptotic activity is regulated through phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin, are involved in its regulation. Alternative splicing results in two transcript variants encoding the same isoform.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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