Thermo Fisher Scientific GALR2 Polyclonal Antibody
GALR2 단백질을 인식하는 Thermo Fisher Scientific의 rabbit polyclonal antibody로, 인간 조직 반응성이 확인됨. 항원 친화 크로마토그래피로 정제되었으며, IHC(P)에서 40 µg/mL로 사용 가능. GPCR 연구 및 신경조직 발현 분석에 적합.
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Thermo Fisher Scientific GALR2 Polyclonal Antibody
Applications and Tested Dilution
- Immunohistochemistry (Paraffin) (IHC (P)): 40 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 18 amino acid peptide from 7th transmembrane domain of human GALR2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2550955 |
Product Specific Information
Percent identity with other species by BLAST analysis:
- Human (100%)
- Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster, Bovine, Horse (94%)
- Panda, Dog, Bat (89%)
Target Information
GalR2 expression is widely documented in the brain and peripheral tissues such as small intestine, heart, kidney, and liver.
Localization data from rat CNS indicate high levels of expression in dorsal root ganglia, amygdala, and Purkinje neurons.
G-protein Coupled Receptors (GPCRs) form one of the largest families of signaling molecules, sharing a structural motif of seven membrane-spanning helices.
They exist in active and inactive forms, with activating ligands inducing conformational changes leading to G-protein signaling.
Negative regulation of GPCRs plays a crucial role in cellular physiology and pharmacological research, with major GPCR-targeted drugs such as Zyprexa (Eli Lilly) and Claritin (Schering-Plough) demonstrating significant therapeutic impact.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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