Thermo Fisher Scientific INCENP Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 785-914 of human INCENP (NP_0646232) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:INCENP,uniProtId:Q9NQS7-1,ncbiNodeId:9606,antigenRange:785-914,antigenLength:918,antigenImageFileName:PA5-87463_INCENP_Q9NQS7-1_Rabbit.svg,antigenImageFileNamePDP:PA5-87463_INCENP_Q9NQS7-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.21 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2804171

Product Specific Information

Immunogen sequence: ALNVTVDVQS PACTSYQMTP QGHRAPPKIN PDNYGMDLNS DDSTDDEAHP RKPIPTWARG TPLSQAIIHQ YYHPPNLLEL FGTILPLDLE DIFKKSKPRY HKRTSSAVWN SPPLQGARVP SSLAYSLKKH; Positive Samples: HeLa, Jurkat, Rat thymus; Cellular Location: Chromosome, Cytoplasm, Nucleus, centromere, cytoskeleton, kinetochore, spindle

Target Information

Chromosomal passenger proteins are members of a group of proteins that move from centromeres to the spindle midzone during mitosis. INCENP (Inner Centromere Protein) is a chromosomal passenger protein with an essential role in mitosis and meiosis. It is a complex highly basic multidomain protein that is dynamically translocated from metaphase chromosomes to the spindle midzone during or just prior to anaphase. Some INCENP transfers to the equatorial cortex before formation of the cleavage furrow. Ultimately, it is discarded in the midbody at the completion of cytokinesis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.