Thermo Fisher Scientific CPS1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

Immunocytochemistry (ICC/IF)

1:50-1:200

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 750-970 of human CPS1 (NP_0018662) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:CPS1,uniProtId:P31327-1,ncbiNodeId:9606,antigenRange:750-970,antigenLength:1500,antigenImageFileName:PA5-109584_CPS1_P31327-1_Rabbit.svg,antigenImageFileNamePDP:PA5-109584_CPS1_P31327-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.26 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.05% ProClin 300

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2854995

Product Specific Information

Immunogen sequence: IKNVVSGKTS ACFEPSLDYM VTKIPRWDLD RFHGTSSRIG SSMKSVGEVM AIGRTFEESF QKALRMCHPS IEGFTPRLPM NKEWPSNLDL RKELSEPSST RIYAIAKAID DNMSLDEIEK LTYIDKWFLY KMRDILNMEK TLKGLNSESM TEETLKRAKE IGFSDKQISK CLGLTEAQTR ELRLKKNIHP WVKQIDTLAA EYPSVTNYLY VTYNGQEHDV N

Target Information

The mitochondrial enzyme encoded by this gene catalyzes synthesis of carbamoyl phosphate from ammonia and bicarbonate. This reaction is the first committed step of the urea cycle, which is important in the removal of excess urea from cells. The encoded protein may also represent a core mitochondrial nucleoid protein. Three transcript variants encoding different isoforms have been found for this gene. The shortest isoform may not be localized to the mitochondrion. Mutations in this gene have been associated with carbamoyl phosphate synthetase deficiency, susceptibility to persistent pulmonary hypertension, and susceptibility to venoocclusive disease after bone marrow transplantation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.