Thermo Fisher Scientific LZTR2 Polyclonal Antibody
Thermo Fisher Scientific의 LZTR2 Polyclonal Antibody는 인간 LZTR2 단백질을 인식하는 토끼 유래 IgG 항체로, Western blot에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 단기 4°C, 장기 -20°C 보관이 권장됩니다. 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein fragment corresponding to a region within amino acids 48–273 of Human LZTR2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.74 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | 0.1M Tris glycine, pH 7, with 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2549311 |
Product Specific Information
- Recommended positive controls: A549, HeLa
- Predicted reactivity: Human (99%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
LZTR2 (also known as RGPR-p117) is a member of the BTB-kelch superfamily and was initially described as a nuclear factor I (NFI) binding protein and transcriptional regulator of the regucalcin gene. LZTR2 is cytoplasmically localized but can translocate to the nucleus via protein kinase C signaling following hormonal stimulation.
Recent studies indicate a correlation between LZTR2 single nucleotide polymorphisms and obesity in the Japanese population, similar to associations observed with TMEM18, GNPDA2, BDNF, FAIM2, and MC4R genes in Caucasian populations. This suggests a potential role of LZTR2 in metabolism and obesity risk.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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