Thermo Fisher Scientific Human APBA2 Synthetic Peptide
인간 APBA2의 아미노 말단 18개 아미노산에 해당하는 합성 펩타이드. 항체 PA5-21053과 함께 차단 펩타이드로 사용 가능. Alzheimer’s disease 및 신경 신호전달 관련 연구에 적합. 고순도 정제, PBS 버퍼에 0.1% BSA 포함.
- 카탈로그번호
- PEP1167
- 판매단위
- pk
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Thermo Fisher Scientific Human APBA2 Synthetic Peptide
Applications
- Control (Ctrl): Assay-dependent
- Blocking Assay (BLOCK): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 18 amino acids near the amino terminus of human APBA2.
PEP-1167 can be used as a blocking peptide with polyclonal antibody PA5-21053.
Target Information
APBA2, a member of the X11 protein family, is a phosphotyrosine-binding domain protein and is a neuronal adapter protein that interacts with amyloid precursor protein (APP) and neuritic plaques in the brains of patients with Alzheimer’s disease. It stabilizes APP and inhibits production of proteolytic APP fragments including the Abeta peptide that is deposited in the brains of Alzheimer’s disease patients.
APBA2 is believed to be involved in signal transduction processes and is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion.
Recent reports suggest that it may also be a candidate gene for autism.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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