Thermo Fisher Scientific PHPT1 Polyclonal Antibody
PHPT1 단백질을 검출하는 Rabbit Polyclonal Antibody로, WB 및 IHC(Paraffin) 실험에 적합합니다. Human, Mouse, Rat 반응성을 가지며, 고순도 Affinity chromatography로 정제되었습니다. 연구용으로만 사용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
- Publications: [References]
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
- Publications: [References]
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human PHPT1 (Accession Q9NRX4), corresponding to amino acid residues A54–I104 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2851766 |
Product Specific Information
Antibody detects endogenous levels of total PHPT1.
Target Information
The protein encoded by this gene is a member of the protein tyrosine phosphatase family. PTPs are signaling molecules that regulate various cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation.
This protein contains a C-terminal PTP domain and an N-terminal domain homologous to the band 4.1 superfamily of cytoskeletal-associated proteins.
P97, a cell cycle regulator involved in membrane-related functions, is a substrate of this PTP.
This PTP interacts with and is regulated by adaptor protein 14-3-3 beta.
Several alternatively spliced transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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