Thermo Fisher Scientific CDH2 Monoclonal Antibody (OTI4G1), TrueMAB
인간 CDH2 단백질을 인식하는 단클론 항체로, Western blot과 유세포분석에 사용 가능. 액상 형태로 1 mg/mL 농도이며, PBS/BSA/glycerol 버퍼에 보관. -20°C에서 보관하며 반복 동결·해동을 피해야 함. 연구용으로만 사용.
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Thermo Fisher Scientific CDH2 Monoclonal Antibody (OTI4G1), TrueMAB
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Flow Cytometry (Flow) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4G1 |
| Immunogen | The extracellular domain of human CDH2 produced in human cells. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
N-cadherin is a 140 kDa transmembrane protein that mediates calcium-dependent intercellular adhesion. It plays a key role in morphogenetic movements during development and regulates cell surface adhesion through homotypic interactions. N-cadherin associates with the actin cytoskeleton via catenin proteins, and this interaction is regulated by phosphorylation of beta-catenin. The protein includes five extracellular cadherin repeats, a transmembrane region, and a conserved cytoplasmic tail, functioning during gastrulation and contributing to left-right asymmetry establishment.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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