Thermo Fisher Scientific RET Proto-oncogene Monoclonal Antibody (RET/2599)
RET 단백질을 인식하는 Mouse monoclonal 항체로, Human 시료에 반응합니다. ELISA 및 Peptide Array에 사용 가능하며, Protein A/G로 정제된 액상 형태입니다. 4°C에서 보관하며, 연구용으로만 사용됩니다.
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Applications
ELISA
- 권장 희석 배수: 2–4 µg/mL
Peptide Array
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | RET/2599 |
| Immunogen | Recombinant fragment (around aa 702–848) of human RET protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage conditions | 4°C, do not freeze |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Target Information
The receptor tyrosine kinase RET is a member of the cadherin superfamily. RET plays a crucial role in neural crest development and can undergo oncogenic activation by cytogenetic rearrangement. RET transduces signals for cell growth and differentiation.
Mutations in the RET gene are associated with multiple endocrine neoplasia type IIA and IIB, Hirschsprung disease, and medullary thyroid carcinoma. Two transcript variants encoding different isoforms have been found for the RET gene. Additional transcript variants have been described but their biological validity has not been confirmed.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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배송/결제/교환/반품 안내
배송 정보
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