Thermo Fisher Scientific KRT6B/KRT6C Polyclonal Antibody
Rabbit polyclonal antibody recognizing human KRT6B/KRT6C. Validated for WB and IHC (Paraffin). Detects endogenous total K2C6B/C. Supplied as liquid, 1 mg/mL, unconjugated. Recommended storage at -20°C. For research use only.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human KRT6C (Accession P48668), corresponding to amino acid residues H11–L61. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2815826 |
Product Specific Information
Antibody detects endogenous levels of total K2C6B/C.
Target Information
Keratins 6 and 16 are expressed in keratinocytes undergoing rapid turnover in the suprabasal region (also known as hyperproliferation-related keratins).
Keratin 6 is found in hair follicles, suprabasal cells of various internal stratified epithelia, and epidermis under both normal and hyperproliferative conditions.
Epidermal injury activates keratinocytes expressing CK6 and CK16. CK6 is strongly expressed in approximately 75% of head and neck squamous cell carcinomas and is particularly associated with differentiation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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