Thermo Fisher Scientific KRT6B/KRT6C Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Product Specifications

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthesized peptide derived from human KRT6C(Accession P48668), corresponding to amino acid residues H11-L61. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Cytokeratin 6,uniProtId:P02538-1,ncbiNodeId:9606,antigenRange:1,antigenLength:564,antigenImageFileName:PA5-100849_Cytokeratin_6_P02538-1_Rabbit.svg,antigenImageFileNamePDP:PA5-100849_Cytokeratin_6_P02538-1_Rabbit_PDP.jpeg,sortOrder:1},{targetFamily:Cytokeratin 6,uniProtId:P48668-1,ncbiNodeId:9606,antigenRange:1|11-61,antigenLength:564,antigenImageFileName:PA5-100849_Cytokeratin_6_P48668-1_Rabbit.svg,antigenImageFileNamePDP:PA5-100849_Cytokeratin_6_P48668-1_Rabbit_PDP.jpeg,sortOrder:2}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Storage conditions

-20°C

Shipping conditions

Wet ice

RRID

AB_2815826

Product Specific Information

Antibody detects endogenous levels of total K2C6B/C.

Target Information

Keratins 6 and 16 are expressed in keratinocytes, which are undergoing rapid turnover in the suprabasal region (also known as hyperproliferation-related keratins). Keratin 6 is found in hair follicles, suprabasal cells of a variety of internal stratified epithelia, in epidermis, in both normal and hyperproliferative situations. Epidermal injury results in activation of keratinocytes which express CK6 and CK16. CK6 is strongly expressed in about 75% of head and neck squamous cell carcinomas. Expression of CK6 is particularly associated with differentiation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.