Thermo Fisher Scientific ALDH7A1 Polyclonal Antibody
인간 ALDH7A1 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, WB, IHC, ICC/IF에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며 액상 형태로 제공됩니다. 연구용으로만 사용되며 변성 및 비변성 조건에서 높은 특이성을 보입니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:1,000–1:2,500 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human ALDH7A1. Recombinant protein control fragment (Product #RP-93154). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2637845 |
Product Specific Information
Immunogen sequence:
DLSLVVPSAL FAAVGTAGQR CTTARRLFIH ESIHDEVVNR LKKAYAQIRV GNPWDPNVLY GPLHTKQAVS MFLGAVEEAK KEGGTVVYGG KVMDRPGNYV EPTIVTGLGH DASIAHTETF APILY
Highest antigen sequence identity to the following orthologs:
- Mouse: 86%
- Rat: 89%
Target Information
The protein encoded by this gene is a member of subfamily 7 in the aldehyde dehydrogenase gene family. These enzymes play a major role in detoxifying aldehydes generated by alcohol metabolism and lipid peroxidation. This member has homology to a protein from the green garden pea (26g pea turgor protein) and is involved in lysine catabolism in the mitochondrial matrix. It is found in both cytosol and mitochondria, likely due to alternative translation initiation sites. An additional isoform variant has been identified. Mutations in this gene are associated with pyridoxine-dependent epilepsy. Several related pseudogenes also exist.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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