Thermo Fisher Scientific LAPTM4B Monoclonal Antibody (CL5289)
인간 LAPTM4B 단백질을 인식하는 Mouse IgG1 단클론 항체로, WB, IHC(P), ICC/IF에 사용 가능. 단백질 A로 정제된 액상형 시약이며, 1 mg/mL 농도로 제공. 암 관련 연구 및 세포 증식, 약물 내성 연구에 적합.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500–1:1,000 |
| Immunocytochemistry (ICC/IF) | 2–10 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | CL5289 |
| Immunogen | Synthetic peptide corresponding to Human LAPTM4B (amino acids 222–236, UniProt ID: Q86VI4-3) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2787053 |
Product Specific Information
Immunogen sequence: EYIRQLPPNF PYRDD
Target Information
LAPTM4B is a multi-pass membrane protein belonging to the LAPTM4/LAPTM5 transporter family. It plays an active role in malignant cell disease progression and is involved in cell proliferation and multidrug resistance. Genetic polymorphism of LAPTM4B is a potential risk factor for colon and gastric cancer development. Research suggests LAPTM4B may serve as a prognostic indicator for ovarian carcinoma and contribute to hepatocellular carcinoma progression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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