Thermo Fisher Scientific NR2C2 Monoclonal Antibody (OTI4B1)
NR2C2 단백질을 인식하는 Mouse monoclonal antibody로, Western blot과 IHC(Paraffin) 분석에 사용 가능. Human 시료에 반응하며, 고순도의 Affinity Chromatography로 정제됨. PBS buffer에 보관되며 -20°C에서 안정적으로 저장 가능.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:2,000 | View 2 publications |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4B1 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–241 of NR2C2 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2724870 |
Target Information
Members of the nuclear hormone receptor family, such as NR2C2, act as ligand-activated transcription factors. These proteins contain:
- An N-terminal transactivation domain
- A central DNA-binding domain with two zinc fingers
- A ligand-binding domain at the C-terminus
Upon activation, the receptor/ligand complex translocates to the nucleus and binds to hormone response elements of target genes.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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