Thermo Fisher Scientific PHF7 Monoclonal Antibody (OTI1C2), TrueMAB
인간 PHF7 단백질(아미노산 155-381)에 특이적인 마우스 단클론 항체. Western blot에 1:2,000 희석으로 검증됨. 액상 형태, 1 mg/mL 농도, PBS/BSA/glycerol 버퍼 포함. 생식세포 분화 연구용으로 적합.
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1C2 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 155–381 of human PHF7 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20 °C, Avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Spermatogenesis is a complex process regulated by extracellular and intracellular factors as well as cellular interactions among interstitial cells of the testis, Sertoli cells, and germ cells. In the testis, this gene is expressed in Sertoli cells but not germ cells. It is absent in patients exhibiting spermatogenic arrest at the spermatocyte stage, leading to oligospermia or azoospermia.
The proteins encoded by this gene contain plant homeodomain (PHD) finger domains, also known as leukemia-associated protein (LAP) domains, believed to be involved in transcriptional regulation. This protein localizes to the nucleus of transfected cells and is implicated in transcriptional regulation of spermatogenesis. Two isoforms are encoded by transcript variants of this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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