Thermo Fisher Scientific GTF3A Monoclonal Antibody (1C6)

Applications

Tested Dilution

Publications

Western Blot (WB)

1-5 µg/mL

-

ELISA (ELISA)

10 ng/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG2b, kappa

Class

Monoclonal

Type

Antibody

Clone

1C6

Immunogen

GTF3A (NP_002088, 185 a.a. approximately 274 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:GTF3A,uniProtId:Q92664-1,ncbiNodeId:9606,antigenRange:185-274,antigenLength:365,antigenImageFileName:H00002971-M08_GTF3A_Q92664-1_House_mouse.svg,antigenImageFileNamePDP:H00002971-M08_GTF3A_Q92664-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

See Label

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Sequence of this protein is as follows: NQQKQYICSF EDCKKTFKKH QQLKIHQCQN TNEPLFKCTQ EGCGKHFASP SKLKRHAKAH EGYVCQKGCS FVAKTWTELL KHVRETHKEE

Target Information

The product of this gene is a zinc finger protein with nine Cis[2]-His[2] zinc finger domains. It functions as an RNA polymerase III transcription factor to induce transcription of the 5S rRNA genes. The protein binds to a 50 bp internal promoter in the 5S genes called the internal control region (ICR), and nucleates formation of a stable preinitiation complex. This complex recruits the TFIIIC and TFIIIB transcription factors and RNA polymerase III to form the complete transcription complex. The protein is thought to be translated using a non-AUG translation initiation site in mammals based on sequence analysis, protein homology, and the size of the purified protein.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.