Thermo Fisher Scientific MGMT Polyclonal Antibody
MGMT 단백질을 표적하는 Thermo Fisher의 Rabbit Polyclonal 항체로, WB, IHC, ICC 등 다양한 응용에 사용 가능. 인간, 마우스, 랫트 반응성. Protein A로 정제된 액상 형태이며, 안정적인 보관을 위해 -20°C 저장.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:300–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:200 |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human MGMT (amino acids 101–207) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
O6-Methylguanine-DNA Methyltransferase (MGMT) is a DNA repair protein that plays a key role in tumor cell resistance to chemotherapeutic alkylating agents. It protects normal cells from genotoxic and carcinogenic effects by removing alkyl groups from the O6 position of guanine. MGMT expression and activity vary widely depending on cell type, tissue, species, and tumor characteristics.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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