Thermo Fisher Scientific POM121 Polyclonal Antibody
POM121 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체. Western blot에 적합하며, 핵공 복합체(NPC) 연구에 유용. 1 mg/mL 액상 형태로 제공되며, -20°C에서 보관. 연구용으로만 사용 가능.
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Applications
- Western Blot (WB): 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide derived from the internal region of human POM121 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2555900 |
Target Information
POM121 (POM121 membrane glycoprotein), also known as POM121A (nuclear envelope pore membrane protein POM 121A), NUP121 (nucleoporin Nup121), or pore membrane protein of 121 kDa, is a 1,249 amino acid single-pass membrane protein that exists as three alternatively spliced isoforms and belongs to the POM121 family.
Encoded by a gene that maps to human chromosome 7q11.23, POM121 is highly conserved and localizes to the nuclear membrane and endoplasmic reticulum membrane.
An essential component of the nuclear pore complex (NPC), POM121 is required for nuclear envelope formation and may play a role in the biogenesis of the NPC. It associates with the central spoke ring complex and helps anchor components of the pore complex to the pore membrane via its F-X-F-G repeat-containing domain. Overexpression of POM121 induces the formation of cytoplasmic annulate lamellae (AL).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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