Thermo Fisher Scientific SEPT9 Polyclonal Antibody
SEPT9 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체로, Western blot, IHC(P), ICC/IF에 적합합니다. 인간, 마우스, 랫트 시료에 반응하며, 고순도 친화크로마토그래피로 정제되었습니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human SEPT9 (Accession Q9UHD8), corresponding to amino acid residues N488–D538 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2815607 |
Product Specific Information
Antibody detects endogenous levels of total SEPT9.
Target Information
The maf oncogene was identified by structural analysis of the AS42 avian transforming retrovirus genome. The Maf family is divided into two subclasses, large Mafs (vMaf, cMaf, MafB, and Nrl) and small Mafs (MafF, MafK, and MafG). Both subclasses contain leucine zipper motifs, allowing homo- and heterodimerization with other bZip transcription factors. Large Mafs include an acidic transactivation domain absent in small Maf proteins.
Small Maf proteins can act as positive regulators of transcription by targeting transcriptionally active dimerization partners to specific DNA elements, or as negative regulators by recruiting repressors or forming inactive homodimers. Human MafF, isolated from a human myometrium cDNA library, encodes a 164-amino acid protein containing an extended leucine zipper and lacking an N-terminal transactivation domain. The three small Maf proteins (MafF, MafK, MafG) are involved in development, differentiation, hematopoiesis, and stress response, regulating stress mechanisms through distinct pathways.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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