Thermo Fisher Scientific NEU1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human NEU1. Recombinant protein control fragment (Product #RP-90541). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:NEU1,uniProtId:Q99519-1,ncbiNodeId:9606,antigenRange:225-353,antigenLength:415,antigenImageFileName:PA5-54430_NEU1_Q99519-1_Rabbit.svg,antigenImageFileNamePDP:PA5-54430_NEU1_Q99519-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.10 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2644622

Product Specific Information

Immunogen sequence: RDGVFCLLSD DHGASWRYGS GVSGIPYGQP KQENDFNPDE CQPYELPDGS VVINARNQNN YHCHCRIVLR SYDACDTLRP RDVTFDPELV DPVVAAGAVV TSSGIVFFSN PAHPEFRVNL TLRWSFSNG

Highest antigen sequence identity to the following orthologs: Mouse - 92%, Rat - 91%.

Target Information

NEU1 is a lysosomal enzyme, which cleaves terminal sialic acid residues from substrates such as glycoproteins and glycolipids. In the lysosome, this enzyme is part of a heterotrimeric complex together with beta-galactosidase and cathepsin A. Mutations in NEU1 gene can lead to sialidosis.The protein encoded by this gene encodes the lysosomal enzyme, which cleaves terminal sialic acid residues from substrates such as glycoproteins and glycolipids. In the lysosome, this enzyme is part of a heterotrimeric complex together with beta-galactosidase and cathepsin A (the latter also referred to as protective protein). Mutations in this gene can lead to sialidosis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.