Thermo Fisher Scientific Human Fibrinogen Native Protein

Applications

Tested Dilution

Publications

Control (Ctrl)

Assay-dependent

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Miscellaneous PubMed (Misc)

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View 2 publications 2 publications

Product Specifications

Species

Human

Published species

Not Applicable

Molecular weight

340 kDa

Class

Native

Type

Protein

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

4.3 mg/mL

Purification

SDS-PAGE

Storage buffer

0.01M sodium phosphate/0.01M sodium citrate, pH 7.3

Contains

no preservative

Storage conditions

-80° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Dry ice

Product Specific Information

RP-43142 contains native human Fibrinogen protein.

RP-43142 may be used as a positive control in many immunological assays.

The product is of human blood/plasma origin. Although the starting material was tested prior to initiation of the manufacturing process, and was found negative or nonreactive for anti-HIV-1/2, HIV-1 antigen(s), HBsAg, STS, anti-HCV, anti-HBcore and anti-HTLV I & II, extreme caution should be used when handling this material as there is a margin of error in all tests.

This product is to be used for IN VITRO research purposes only, and is not intended for clinical or diagnostic use!

Target Information

Fibrinogen, the precursor of fibrin, is the coagulable protein in the blood plasma of vertebrates. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. Fibrinogen consists as a dimer of 3 pairs of non-identical chains FGA, FGB, and FGG that are cross-linked by disulfide bonds in their N-terminal segments. The molecule has 2 terminal D domains and one central E domain, all three domains are separated when fibrinogen is degradated by plasmin. Mutations in this gene lead to several disorders, including dysfibrinogenemia, afibrinogenemia, and renal amyloidosis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.