Thermo Fisher Scientific FBXL22 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human FBXL22. Recombinant protein control fragment (Product #RP-98192). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:FBXL22,uniProtId:Q6P050-1,ncbiNodeId:9606,antigenRange:180-247,antigenLength:247,antigenImageFileName:PA5-62992_FBXL22_Q6P050-1_Rabbit.svg,antigenImageFileNamePDP:PA5-62992_FBXL22_Q6P050-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.2 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2641535

Product Specific Information

Immunogen sequence: ERPSETPPAP GVSWGPPPPG APVVISVKQE EGKQGRTGRR SHRAAPPCGF ARTRVCPPTF PGADAFPQ

Highest antigen sequence identity to the following orthologs: Mouse - 37%, Rat - 36%.

Target Information

Members of the F-box protein family, such as FBXL22, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.