Thermo Fisher Scientific FBXL22 Polyclonal Antibody
Rabbit polyclonal antibody against human FBXL22 protein. Validated for IHC (Paraffin) with dilution range 1:50–1:200. Purified by antigen affinity chromatography and supplied in PBS with 40% glycerol. Suitable for research use only.
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Applications
Tested Dilution
- Immunohistochemistry (Paraffin) (IHC (P)): 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human FBXL22. Recombinant protein control fragment (Product #RP-98192). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2641535 |
Product Specific Information
Immunogen sequence:
ERPSETPPAP GVSWGPPPPG APVVISVKQE EGKQGRTGRR SHRAAPPCGF ARTRVCPPTF PGADAFPQ
Highest antigen sequence identity to the following orthologs:
- Mouse: 37%
- Rat: 36%
Target Information
Members of the F-box protein family, such as FBXL22, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box and with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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