Thermo Fisher Scientific CBX6 Polyclonal Antibody
CBX6 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, IHC, IP에 적합합니다. 액상 형태로 제공되며 4°C에서 보관합니다. FFPE 조직의 IHC 시 citrate buffer(pH 6.0) 전처리를 권장합니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunohistochemistry (IHC) | 1:500–1:2,000 |
| Immunoprecipitation (IP) | 2–5 µg/mg lysate |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Between amino acids 250 and 300 of CBX6 (UniProt ID: O95503-1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Application Note: For IHC, epitope retrieval with citrate buffer (pH 6.0) is recommended for FFPE tissue sections.
Target Information
Polycomb group (PcG) proteins form multiprotein complexes that regulate expression patterns of developmental and cell proliferation genes.
CBX6 (chromobox protein homolog 6) is a 412 amino acid protein that is a component of the chromatin-associated PcG complex.
Through interaction with PcG, CBX6 modifies chromatin and maintains the transcriptionally repressive state of genes.
Members of the chromobox domain protein family are characterized by the presence of a 37 amino acid chromobox (CHRomatin Organization MOdifier) domain, which plays a mechanistic role in targeting chromodomain proteins to specific regions of the nucleus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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