Thermo Fisher Scientific Bcl-xS Polyclonal Antibody
Bcl-xS 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western blot, IHC, IP 등 다양한 응용에 적합합니다. Human, Mouse, Rat 반응성이 있으며, 항원 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution | References |
|---|---|---|
| Western Blot (WB) | 1:500–1:3,000 | – |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 | – |
| Immunoprecipitation (IP) | Assay-dependent | – |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to a region within amino acids 72–160 of Bcl-xS |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1M Tris glycine, pH 7, with 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2549676 |
Product Specific Information
- Recommended positive controls: A549, H1299, HCT116, MCF-7, PC-12, Rat2
- Store product as a concentrated solution.
- Centrifuge briefly prior to opening the vial.
Target Information
The protein encoded by this gene belongs to the BCL-2 protein family, which regulates apoptosis through hetero- or homodimer formation. These proteins are located at the outer mitochondrial membrane and control VDAC channel opening, influencing mitochondrial membrane potential, reactive oxygen species production, and cytochrome C release. Two alternatively spliced transcript variants exist: the longer isoform acts as an apoptotic inhibitor, while the shorter form (Bcl-xS) acts as an apoptotic activator.
⚠ WARNING: This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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