Thermo Fisher Scientific CBFA2T3 Polyclonal Antibody
Rabbit polyclonal antibody targeting human CBFA2T3 protein for Western blot and immunoprecipitation. Recognizes residues 603–653 of the Runt Domain alpha subunit 2. Supplied as unconjugated liquid form at 1 mg/mL, stored at 4°C. For research use only.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 2–10 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 603 and 653 of human Core-Binding Factor, Runt Domain, alpha subunit 2; translocated to, 3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
This gene encodes a member of the myeloid translocation gene family which interacts with DNA-bound transcription factors and recruits a range of corepressors to facilitate transcriptional repression.
The t(16;21)(q24;q22) translocation is one of the less common karyotypic abnormalities in acute myeloid leukemia.
This translocation produces a chimeric gene composed of the 5′ region of the runt-related transcription factor 1 gene fused to the 3′ region of this gene.
This gene is also a putative breast tumor suppressor.
Alternative splicing results in transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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