Thermo Fisher Scientific Importin 4 Polyclonal Antibody
Human Importin 4 단백질을 인식하는 Rabbit polyclonal antibody로, WB 및 IHC(P) 실험에 적합. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol buffer에 저장. 핵단백질 수입 관련 연구용으로 사용.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human Importin 4. Recombinant protein control fragment (Product #RP-97613). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.4 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2642714 |
Product Specific Information
Immunogen sequence:
AFLPYMESVF EEVFKLLECP HLNVRKAAHE ALGQFCCALH KACQSCPSEP NTAALQAALA RVVPSYMQAV NRERERQVVM AVLE
Highest antigen sequence identity to orthologs:
- Mouse: 69%
- Rat: 77%
Target Information
Importin-4 is a protein encoded by the human IPO4 gene.
Functions as a nuclear transport receptor mediating import of nuclear localization signal (NLS)-containing cargo proteins.
Facilitates docking to the nuclear pore complex (NPC) via nucleoporin binding and translocation through the pore in a Ran-dependent manner.
At the nucleoplasmic side, Ran binding causes dissociation of the importin/substrate complex and re-export of importin to the cytoplasm.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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