Thermo Fisher Scientific MTCH2 Polyclonal Antibody
MTCH2 단백질을 인식하는 Rabbit Polyclonal 항체로 Western blot 및 IHC(P) 분석에 적합. Human 및 Mouse 반응성 검증. Protein A 및 Antigen affinity chromatography로 정제. PBS buffer, 0.09% sodium azide 함유. 연구용 전용 제품.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000 | View 2 publications |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:100 | – |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide between 75–103 amino acids from the N-terminal region of human MTCH2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2542906 |
Target Information
MTCH2 is a member of the mitochondrial carrier protein family that catalyzes the exchange of substrates across the inner mitochondrial membrane. It is targeted by Bid, a pro-apoptotic Bcl-2 family member, in response to apoptotic signals, suggesting that MTCH2 may play a key role in the mitochondrial apoptosis pathway. Apoptosis is essential for normal development, tissue homeostasis, and the removal of damaged cells. Dysregulation of this process has been linked to various diseases, including cancer. The Bcl-2 family of proteins includes both apoptosis inhibitors and promoters.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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