Thermo Fisher Scientific NR1I3 Monoclonal Antibody (OTI9E4), TrueMAB
인간 NR1I3 단백질(아미노산 1-236)을 인식하는 마우스 단일클론 항체. Western blot에 적합하며, 무보존제·동결건조 형태로 제공. 약물 및 빌리루빈 대사 관련 핵수용체 연구용에 최적화됨.
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Applications
- Western Blot (WB)
Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI9E4 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–236 of human NR1I3 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
This gene encodes a member of the nuclear receptor superfamily and regulates xenobiotic and endobiotic metabolism.
The protein binds DNA as a monomer or heterodimer with the retinoid X receptor, controlling transcription of genes involved in drug metabolism and bilirubin clearance (e.g., cytochrome P450 family).
Unlike most nuclear receptors, this transcriptional regulator is constitutively active without ligand but can be modulated by agonists and inverse agonists.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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