Thermo Fisher Scientific CD49a Monoclonal Antibody (TS2/7)

Applications

Tested Dilution

Publications

Western Blot (WB)

Assay-dependent

-

Immunohistochemistry (IHC)

-

View 2 publications 2 publications

Immunohistochemistry (Frozen) (IHC (F))

Assay-dependent

-

Flow Cytometry (Flow)

Assay-dependent

View 3 publications 3 publications

Immunoprecipitation (IP)

Assay-dependent

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human

Published species

Human

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

TS2/7

Immunogen

Human VLA-1 antigen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

20 µg/mL

Purification

Protein G

Storage buffer

PBS with 0.5% BSA

Contains

0.1% sodium azide

Storage conditions

-20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_223629

Product Specific Information

MA49A0 targets CD49a in FACS, IHC(F), IP, and WB applications and shows reactivity with Human samples.

The MA49A0 immunogen is human VLA-1 antigen.

MA49A0 detects CD49a which has a predicted molecular weight of approximately 128 kDa.

Target Information

Integrin alpha 1 (ITGA1) chain associates with the beta 1 (ITGB1) chain to form a heterodimer that functions as a dual laminin/collagen receptor in neural cells and hematopoietic cells. ITGA1 has a 206-amino acid I domain in its N-terminal half, followed by 3 divalent cation-binding sites and a C-terminal transmembrane domain with a short cytoplasmic tail. It also has 28 potential N-glycosylation sites. Human ITGA1 was expressed in a mouse fibroblast cell line as a 180-kD protein. ITGA1 is involved in the early remodeling of osteoarthritic cartilage and plays an essential role in the regulation of mesenchymal stem cell proliferation and cartilage production. It also plays an essential role in the regulation of MSC proliferation and cartilage production.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.