Thermo Fisher Scientific CD49a Monoclonal Antibody (TS2/7)
CD49a 단백질 검출용 Mouse IgG1 단일클론 항체로, Human 시료에 반응하며 WB, IHC, Flow, IP 등에 사용 가능. 비결합형 액상 형태로, Protein G 정제 및 PBS/BSA buffer에 보존. 세포 부착 및 신호전달 연구에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | Assay-dependent | - |
| Immunohistochemistry (IHC) | - | 2 publications |
| Immunohistochemistry (Frozen) (IHC(F)) | Assay-dependent | - |
| Flow Cytometry (Flow) | Assay-dependent | 3 publications |
| Immunoprecipitation (IP) | Assay-dependent | 1 publication |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | TS2/7 |
| Immunogen | Human VLA-1 antigen |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 20 µg/mL |
| Purification | Protein G |
| Storage Buffer | PBS with 0.5% BSA |
| Contains | 0.1% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_223629 |
Product Specific Information
MA49A0 targets CD49a in FACS, IHC(F), IP, and WB applications and shows reactivity with Human samples.
The MA49A0 immunogen is human VLA-1 antigen.
MA49A0 detects CD49a, which has a predicted molecular weight of approximately 128 kDa.
Target Information
Integrin alpha 1 (ITGA1) chain associates with the beta 1 (ITGB1) chain to form a heterodimer functioning as a dual laminin/collagen receptor in neural and hematopoietic cells.
ITGA1 contains a 206-amino acid I domain in its N-terminal half, three divalent cation-binding sites, and a C-terminal transmembrane domain with a short cytoplasmic tail.
It also has 28 potential N-glycosylation sites. Human ITGA1 was expressed in a mouse fibroblast cell line as a 180-kD protein.
ITGA1 is involved in early remodeling of osteoarthritic cartilage and plays a crucial role in regulating mesenchymal stem cell proliferation and cartilage production.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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