Thermo Fisher Scientific 2-hydroxyisobutyryl-Histone H1.2 (Lys63) Polyclonal Antibody
Human Histone H1.2의 Lys63 위치에서 2-hydroxyisobutyrylation을 인식하는 Rabbit Polyclonal Antibody. ICC/IF 및 ELISA에 사용 가능. 항원 친화 정제 방식으로 제조되어 높은 특이성과 재현성을 제공. 연구용으로만 사용 가능.
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:50–1:200
ELISA
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide sequence around site of 2-hydroxyisobutyryl-Lys (63) derived from Human Histone H1.2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.08 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.03% Proclin 300 |
| Storage conditions | -20°C or -80°C if preferred |
| Shipping conditions | Wet ice |
| RRID | AB_3091508 |
Target Information
Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone H1 interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H1 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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