Thermo Fisher Scientific FGD1 Polyclonal Antibody
FGD1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체. Western blot에 적합하며 인간 시료에 반응. 합성 펩타이드 면역원 사용. 고순도 친화 크로마토그래피 정제, 액상 형태로 제공.
- 카탈로그번호
- PA541477
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 0.2–1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the N-terminal of human FGD1 (aa 2–51) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2608210 |
Product Specific Information
Peptide sequence:
HGHRAPGGAG PSEPEHPATN PPGAAPPACA DSDPGASEPG LLARRGSGSA
Sequence homology:
- Cow: 86%
- Human: 100%
- Pig: 86%
- Rat: 79%
Target Information
FGD1 contains Dbl (DH) and pleckstrin (PH) homology domains. It binds specifically to the Rho family GTPase Cdc42Hs and stimulates GDP-GTP exchange of the isoprenylated form of Cdc42Hs. It also activates the mitogen-activated protein kinase cascade leading to c-Jun kinase SAPK/JNK1 activation.
FGD1 plays an essential role in embryonic development, and mutations in the FGD1 gene result in Aarskog-Scott syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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