Thermo Fisher Scientific CDC20 Polyclonal Antibody
CDC20 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, 인간 및 생쥐에 반응. IHC 및 IHC(P) 실험에 적합하며, 항원 친화 크로마토그래피로 정제됨. 연구용으로만 사용.
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Applications
Immunohistochemistry (IHC)
- Tested Dilution: 1:100–1:500
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 50 and 100 of human cell division cycle 20 (CDC20) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.50 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | TBS, pH 7.0–8.0, with 0.1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Predicted to react with Dog, Horse, Guinea pig, Pig, Panda, Orangutan, Monkey, Gorilla, Chimpanzee, Small-eared galago, and Naked mole rat (based on 100% sequence identity)
Target Information
CDC20 is required for full ubiquitin ligase activity of the anaphase promoting complex/cyclosome (APC/C) and may confer substrate specificity upon the complex. It is regulated by MAD2L1: in metaphase, the MAD2L1-CDC20-APC/C ternary complex is inactive, and in anaphase, the CDC20-APC/C binary complex is active in degrading substrates. The CDC20-APC/C complex positively regulates synaptic vesicle clustering at the presynaptic membrane in postmitotic neurons. CDC20-APC/C-induced degradation of NEUROD2 induces presynaptic differentiation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지: IHC-00232_CDC20_Q12834-1_Rabbit.svg)
(이미지: IHC-00232_CDC20_Q12834-1_Rabbit_PDP.jpeg)
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