Thermo Fisher Scientific TXNRD1 Monoclonal Antibody (OTI5G3), TrueMAB

Thermo Fisher Scientific TXNRD1 Monoclonal Antibody (OTI5G3), TrueMAB

Applications

• Western Blot (WB): 1:500–1:2,000 dilution

Species Reactivity

• Human
• Mouse
• Rat

Host / Isotype

• Mouse / IgG1

Class

• Monoclonal

Type

• Antibody

Clone

• OTI5G3

Immunogen

Full length human recombinant protein of human TXNRD1 produced in E. coli.

Conjugate

• Unconjugated

Form

• Lyophilized

Concentration

• 1 mg/mL

Purification

• Affinity chromatography

Storage Buffer

• PBS, pH 7.3, with 8% trehalose

Contains

• No preservative

Storage Conditions

• −20°C, avoid freeze/thaw cycles

Shipping Conditions

• Ambient (domestic)
• Wet ice (international)

Product Specific Information

For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL (Product #89882).

Target Information

TXNRD1 encodes a pyridine nucleotide oxidoreductase that reduces thioredoxins and other substrates, playing key roles in selenium metabolism and oxidative stress protection.
The active enzyme is a homodimer utilizing FAD as a cofactor, each subunit containing a selenocysteine (Sec) residue essential for catalytic activity.
Sec is encoded by the UGA codon, normally a stop signal, but recognized as Sec due to the SECIS element in the 3′ UTR.
Alternative splicing produces multiple transcript variants encoding similar or distinct isoforms.

For Research Use Only. Not for use in diagnostic procedures or resale without authorization.