Thermo Fisher Scientific C2 Polyclonal Antibody
Thermo Fisher Scientific의 C2 Polyclonal Antibody는 인간 C2 단백질을 표적으로 하는 토끼 유래 IgG 항체입니다. WB 및 IHC(P) 실험에 적합하며, 항원 친화 크로마토그래피로 정제되었습니다. 액상 형태로 제공되며, 안정적인 저장을 위해 PBS와 50% 글리세롤 버퍼에 보존됩니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.5–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 5–20 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein Complement Component 2 (amino acids 245–451 of the target protein) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.88 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2903546 |
Target Information
Component C2 is a serum glycoprotein that functions as part of the classical pathway of the complement system. Activated C1 cleaves C2 into C2a and C2b. The serine proteinase C2a then combines with complement factor 4b to form the C3 or C5 convertase.
Deficiency of C2 has been reported to be associated with certain autoimmune diseases, and SNPs in this gene have been linked to altered susceptibility to age-related macular degeneration.
This gene localizes within the class III region of the MHC on the short arm of chromosome 6. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described, but their full-length sequences have not been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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