
Thermo Fisher Scientific BAG5 Monoclonal Antibody (OTI4E12), TrueMAB
Human BAG5 단백질을 인식하는 Mouse IgG1 단일클론 항체로 Western Blot에 적합. 고순도 Affinity chromatography 정제, 액상 형태로 안정적 저장 가능. 신경세포 사멸 및 hsp70 상호작용 연구에 활용.
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Applications
- Western Blot (WB): 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4E12 |
| Immunogen | Full length human recombinant protein of human BAG5 produced in 293T |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
It has been hypothesized that the BAG-5 protein may induce the death of nigral neurons through its predicted interaction with hsp70, leading to increased protein aggregation and cell death by disinhibition of hsp70’s anti-apoptotic function. BAG-5 is believed to play an important role in neuronal death mechanisms and may act as a modulator of the hsp70/hsp40 chaperone axis or through BAG-BAG heterodimerization with other BAG-containing proteins.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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