Thermo Fisher Scientific BAG5 Monoclonal Antibody (OTI4E12), TrueMAB

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

OTI4E12

Immunogen

Full length human recombinant protein of human BAG5 produced in 293T. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:BAG5,uniProtId:Q9UL15-1,ncbiNodeId:9606,antigenRange:1-447,antigenLength:447,antigenImageFileName:TA810632_BAG5_Q9UL15-1_House_mouse.svg,antigenImageFileNamePDP:TA810632_BAG5_Q9UL15-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS with 1% BSA, 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Target Information

It has been hypothesizes that the BAG-5 protein will induce the death of nigral neurons through its predicted interaction with hsp70, which will cause increased protein aggregation and cell death by disinhibition of hsp70`s anti-apoptotic function. It is believed that BAG-5 will play an important role in the mechanisms of neuronal death. BAG-5 may also be of interest due to its possible role as a modulator of the hsp70/hsp40 chaperone axis or its possible interaction and coordination of localization/ modulation of other BAG containing proteins via BAG-BAG heterodimerization.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.