Thermo Fisher Scientific PHEX Polyclonal Antibody
PHEX 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체. Western Blot에 적합하며, 인간 시료 반응성. Protein A 및 항원 친화 크로마토그래피로 정제. PBS buffer에 보관하며, 연구용으로만 사용 가능.
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Applications
- Western Blot (WB): 1:1,000 dilution
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide between 567–595 amino acids from the C-terminal region of human PHEX |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2900882 |
Target Information
Peptidase that cleaves SIBLING (small integrin-binding ligand, N-linked glycoprotein)-derived ASARM peptides, thus regulating their biological activity.
Cleaves ASARM peptides between Ser and Glu or Asp residues.
Regulates osteogenic cell differentiation and bone mineralization through the cleavage of the MEPE-derived ASARM peptide.
Promotes dentin mineralization and renal phosphate reabsorption by cleaving DMP1- and MEPE-derived ASARM peptides.
Inhibits the cleavage of MEPE by CTSB/cathepsin B thus preventing MEPE degradation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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