Thermo Fisher Scientific GPX1 Polyclonal Antibody
Thermo Fisher Scientific의 GPX1 Polyclonal Antibody는 인간, 마우스, 랫트 시료에서 GPX1 단백질 검출에 적합한 Rabbit Polyclonal 항체입니다. Western blot, IHC, ICC, Flow Cytometry 등에 사용 가능하며, 고순도의 Protein A 및 항원 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용됩니다.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:2,000 | View 5 publications |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:10–1:50 | – |
| Immunocytochemistry (ICC/IF) | 1:10–1:50 | – |
| Flow Cytometry (Flow) | 1:25 | – |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Human, Mouse, Rat |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide between 164–193 amino acids from the C-terminal region of human GPX1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2.0 mg/mL |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2543823 |
Target Information
Glutathione peroxidases (GPXs) are ubiquitously expressed enzymes that catalyze the reduction of hydrogen peroxide and organic hydroperoxides using glutathione. Several isoforms exist, differing in structure and localization.
- GPX1 (cGPX): Cytosolic/mitochondrial, selenium-dependent enzyme, first identified member of the GPX family.
- GPX2 (GI-GPX): Expressed in gastrointestinal epithelium.
- GPX3 (pGPX): Extracellular plasma form, mainly produced by the kidney and secreted into the bloodstream.
- GPX4 (PH-GPX): Reduces hydroperoxides in membranes and lipoproteins.
Most mammalian GPX isoforms, except for Cys-containing GPX3 and GPX5, contain selenocysteine at their active site.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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