Thermo Fisher Scientific Frataxin Monoclonal Antibody (FXN, 2124)
Frataxin(FXN) 단백질 검출용 Mouse 단클론 항체로 Western blot, IHC 등 다양한 응용에 적합함. 인간 시료 반응성, Protein A/G 정제, PBS buffer 기반 액상 형태. 미토콘드리아 철 수송 및 Friedreich ataxia 연구에 활용 가능.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1–2 µg/mL |
| Peptide Array (Array) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | FXN, 2124 |
| Immunogen | Recombinant fragment of human Frataxin (FXN) protein (around aa 57–210) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Immunohistochemistry (PFA fixed): Incubate antibody for 30 minutes at room temperature.
Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA (pH 9.0) for 45 minutes at 95°C, followed by cooling at room temperature for 20 minutes.
Target Information
FXN is a mitochondrial protein belonging to the FRATAXIN family.
It regulates mitochondrial iron transport and respiration.
Expansion of the intronic trinucleotide repeat GAA results in Friedreich ataxia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지 파일명: 2395-MSM4-P1ABX_FXN_Q16595-1_House_mouse.svg, 2395-MSM4-P1ABX_FXN_Q16595-1_House_mouse_PDP.jpeg)
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