Thermo Fisher Scientific Human TMEM88 Synthetic Peptide
Human TMEM88 단백질의 C-말단 19개 아미노산 서열을 기반으로 한 합성 펩타이드. TMEM88 항체의 블로킹 실험에 사용 가능. Wnt/β-catenin 신호 조절 연구용으로 적합. 고순도 정제, 액상 형태로 제공.
- 카탈로그번호
- PEP1278
- 판매단위
- pk
카탈로그
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 19 amino acids near the carboxy terminus of human TMEM88.
PEP-1278 can be used as a blocking peptide with polyclonal antibody PA5-21164.
Target Information
Transmembrane protein 88 (TMEM88) is a two-transmembrane-type protein whose C-terminal tail binds the PDZ domain of Dishevelled (Dvl), a key component in Wnt signaling pathways.
TMEM88 attenuates Wnt/β-catenin signaling induced by Wnt-1 ligand in a dose-dependent manner, and knockdown of TMEM88 by RNAi increases Wnt activity.
These findings suggest that TMEM88 plays a role in regulating Wnt signaling in a context-dependent manner.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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