Thermo Fisher Scientific Claudin 6 Polyclonal Antibody
Claudin 6 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC, ICC/IF, ELISA 등 다양한 응용에 적합합니다. Human, Mouse, Rat 시료에 반응하며, Protein A로 정제된 고순도 항체입니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:500 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human Claudin 6, amino acids 111–220 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | –20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Tight junctions are specialized structures that enable cell-to-cell adhesion in epithelial or endothelial sheets, forming continuous seals and acting as barriers to solute and water passage through the paracellular space. Claudin 6 is an integral membrane protein and a member of the claudin family, contributing to tight junction strand formation. It also serves as one of the entry cofactors for hepatitis C virus. Gene methylation of Claudin 6 may be associated with esophageal tumorigenesis. The CLDN6 gene is located adjacent to CLDN9 on chromosome 16.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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