Thermo Fisher Scientific HDAC1 Monoclonal Antibody (1061CT1.3.1)
HDAC1 단백질을 인식하는 Mouse IgM 단일클론 항체로 Western blot에 적합합니다. 인체 반응성을 가지며, 비결합형 상태로 제공됩니다. 유전자 발현 조절 및 세포 성장 연구에 활용됩니다. 연구용으로만 사용 가능합니다.
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Thermo Fisher Scientific HDAC1 Monoclonal Antibody (1061CT1.3.1)
Applications
- Western Blot (WB)
Tested Dilution: 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgM, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1061CT1.3.1 |
| Immunogen | Purified His-tagged HDAC1 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2 mg/mL |
| Purification | Euglobulin precipitation |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2897546 |
Target Information
Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. HDAC1 belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It interacts with the retinoblastoma tumor-suppressor protein, forming a key complex in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, HDAC1 deacetylates p53 and modulates its effect on cell growth and apoptosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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