Thermo Fisher Scientific ganglioside GM1 Polyclonal Antibody
Rabbit polyclonal antibody against ganglioside GM1. 다양한 면역분석(IHC, ICC, Flow, ELISA)에 사용 가능. 고순도 액상 형태, 1 mg/mL 농도. 연구용으로만 사용, 진단용 불가.
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Applications and Tested Dilutions
| Application | Tested Dilution / Amount |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| Flow Cytometry (Flow) | 0.2 µg |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated purified pig GM1 ganglioside |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Asialo ganglio-N-tetraosylceramide (asialo-GM1) is a glycolipid found on human, mouse, rat, bovine, and hamster cells. Glycolipids are defined by specific transferases that modify the lipid and can serve as immune cell response targets. Auto-antibodies against these molecules have been identified, and they may act as co-receptors for pathogens.
Asialo-GM1 is expressed on NK cells and a subset of monocyte/macrophages in mouse spleen, as well as in rat and bovine brain, fetal liver, and immature thymocytes. Expression levels may increase with tumor progression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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